Bute can usually be administered for 5-7 days with no adverse effects. If a continued treatment regime is required, it may be necessary to co-treat with omeprazole and/or sucralfate, to provide gastrointestinal protection.
Sucralfate works by coating the stomach and small intestine with a protective layer; this protective barrier replaces the enzyme protectant that is blocked by Bute. Omeprazole heals gastric ulcers caused by using Bute.
The content of this article should not be considered, or used as a substitute for, veterinary medical advice, diagnosis or treatment.